ICON GOVERNMENT AND PUBLIC HEALTH SOLUTIONS, INC. - A PHASE 1 TRIAL TO EVALUATE AN ORALLY INGESTED PROBIOTIC YEAST GENETICALLY MODIFIED TO EXPRESS A TETRA-SPECIFIC ANTI-TOXIN FOR CLOSTRIDIOIDES DIFFICILE

On Dec 9, 2025, Department of Health and Human Services obligated $2,514,022 to ICON GOVERNMENT AND PUBLIC HEALTH SOLUTIONS, INC. for a phase 1 trial to evaluate an orally ingested probiotic yeast genetically modified to express a tetra-specific anti-toxin for clostridioides difficile. The award is classified under NAICS 541715 — RESEARCH AND DEVELOPMENT IN THE PHYSICAL, ENGINEERING, AND LIFE SCIENCES (EXCEPT NANOTECHNOLOGY AND BIOTECHNOLOGY) and issued as a cost plus fixed fee contract. Competition extent: full and open competition with 1 offer received. Performance is located in BLUE BELL, PA. The contract is scheduled through Jan 13, 2032. This award is one of several similar procurements from Department of Health and Human Services under NAICS 541715 — related awards are listed below.